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Denis M Grant Selected Research

4-biphenylamine

1/2020The impact of sex on hepatotoxic, inflammatory and proliferative responses in mouse models of liver carcinogenesis.
1/2019Primary aromatic amines and cancer: Novel mechanistic insights using 4-aminobiphenyl as a model carcinogen.
12/2016Influence of sex and developmental stage on acute hepatotoxic and inflammatory responses to liver procarcinogens in the mouse.
4/2015N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer.
6/2012Influence of arylamine N-acetyltransferase, sex, and age on 4-aminobiphenyl-induced in vivo mutant frequencies and spectra in mouse liver.

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Denis M Grant Research Topics

Disease

7Neoplasms (Cancer)
01/2019 - 10/2007
3Fatty Liver
01/2021 - 07/2015
3Wasting Syndrome (Wasting Disease)
05/2019 - 07/2015
3Carcinogenesis
01/2019 - 07/2003
2Inflammation (Inflammations)
01/2022 - 01/2021
2Liver Neoplasms (Liver Cancer)
01/2020 - 04/2015
2Hepatocellular Carcinoma (Hepatoma)
07/2015 - 04/2015
1Colitis
01/2022
1Body Weight (Weight, Body)
01/2022
1Hypoxia (Hypoxemia)
11/2021
1Breast Neoplasms (Breast Cancer)
11/2021
1Chylous Ascites
05/2019
1Atrophy
10/2018
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
10/2015
1Cardiovascular Diseases (Cardiovascular Disease)
10/2015
1Autoimmune Hepatitis
06/2014
1Liver Diseases (Liver Disease)
08/2013

Drug/Important Bio-Agent (IBA)

54-biphenylamineIBA
01/2020 - 06/2012
4Polychlorinated Dibenzodioxins (TCDD)IBA
01/2021 - 07/2015
4EnzymesIBA
01/2019 - 07/2003
3Proteins (Proteins, Gene)FDA Link
01/2022 - 06/2014
3CarcinogensIBA
01/2019 - 06/2012
3DNA (Deoxyribonucleic Acid)IBA
07/2015 - 05/2012
3N-acetyltalosaminuronic acid (NAT)IBA
06/2012 - 10/2007
2Interleukin-6 (Interleukin 6)IBA
01/2022 - 12/2016
2ADP Ribose Transferases (ADP Ribosyltransferase)IBA
11/2021 - 07/2015
2Diethylnitrosamine (N-Nitrosodiethylamine)IBA
01/2020 - 12/2016
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
05/2019 - 07/2015
2Pharmaceutical PreparationsIBA
01/2019 - 08/2013
2DNA AdductsIBA
01/2019 - 04/2015
2DioxinsIBA
10/2018 - 07/2015
2Cytochrome P-450 CYP1A2 (CYP1A2)IBA
07/2015 - 06/2012
2Cytochrome P-450 CYP2E1 (CYP2E1)IBA
07/2015 - 04/2015
2AcetyltransferasesIBA
06/2014 - 06/2012
1Dextran SulfateIBA
01/2022
1InterleukinsIBA
01/2022
1Lipocalin-2IBA
01/2022
1LigandsIBA
01/2022
1ChemokinesIBA
01/2022
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
11/2021
1Estrogen ReceptorsIBA
11/2021
1XenobioticsIBA
01/2021
1MethylcholanthreneIBA
05/2019
1AminesIBA
01/2019
1Alanine Transaminase (SGPT)IBA
10/2018
1LipidsIBA
10/2018
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
10/2018
1Caffeine (No Doz)FDA LinkGeneric
10/2015
1CoffeeFDA Link
10/2015
1AntioxidantsIBA
04/2015
1Isonicotinic Acids (Isonicotinic Acid)IBA
06/2014
1Freund's AdjuvantIBA
06/2014
1Isoniazid (Ftivazide)FDA LinkGeneric
06/2014
1A-Form DNA (A-DNA)IBA
06/2012
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
06/2012
1Arylamine N-AcetyltransferaseIBA
05/2012

Therapy/Procedure

1Therapeutics
08/2013